Which of the following vaccines uses an organism to produce antigens via DNA plasmid insertion?

A Naked DNA Vaccine utilizes a particular technique where DNA plasmids containing the genetic material of an antigen are inserted into host cells. This process prompts the host cells to produce the antigen, which then stimulates an immune response. The DNA is introduced into cells, often through methods like electroporation or chemical techniques. Once the antigen is produced, the immune system recognizes it as foreign and mounts a response, leading to the development of immunity.

In contrast, the other types of vaccines function differently. Toxoid vaccines involve inactivated toxins, Killed vaccines use whole microbes that have been killed or inactivated, and Attenuated vaccines use live pathogens that have been weakened so they do not cause disease. None of these methods involve the direct insertion of DNA plasmids to produce antigens, which is the defining characteristic of Naked DNA Vaccines.